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Mouse Anti-GABARAP/Gold Conjugated antibody (bsm-51134M-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bsm-51134M-Gold
英文名稱 Mouse Anti-GABARAP/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的小鼠抗γ-氨基丁酸受體相關(guān)蛋白單克隆抗體
別    名 ATG8A; FLC 3B; FLC3B; FLJ25768; GABA(A) receptor associated protein; GABA(A) receptor-associated protein; GABARAP a; GABARAP; Gamma aminobutyric acid receptor associated protein; Gamma-aminobutyric acid receptor-associated protein; GBRAP_HUMAN; MGC120154; MGC120155; MM 46; MM46.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  G蛋白信號  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 10B2
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 Recombinant human GABARAP protein
亞    型 IgG1
純化方法 affinity purified by Protein G
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]

Function:
May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.

Subunit:
Interacts with GPHN and NSF. Interacts with GABRG2, beta-tubulin and ULK1. Interacts with CALR. Interacts with DDX47. Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25.

Subcellular Location:
Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Largely associated with intracellular membrane structures including the Golgi apparatus and post-synaptic cisternae. Colocalizes with microtubules.

Tissue Specificity:
Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the MAP1 LC3 family.

Database links:

Entrez Gene: 11337 Human

Entrez Gene: 56486 Mouse

Entrez Gene: 58974 Rat

Omim: 605125 Human

SwissProt: O95166 Human

SwissProt: Q9DCD6 Mouse

SwissProt: P60517 Rat

Unigene: 647421 Human

Unigene: 272460 Mouse

Unigene: 8411 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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