| 產品介紹 |
background:
LRRC25 is a 305 amino acid protein that contains two LRR repeats. LRRC25 is a single-pass type I membrane protein that is expressed in monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, plasmacytoid dendritic cells (PDC), B-lymphocytes, peripheral blood leukocytes, spleen and bone marrow, with lower levels in lymph nodes, fetal liver, and appendix. LRRC25 may play a role in the activation of cells of innate and acquired immunity.
Function:
LRRC25 is a single-pass type I membrane protein. It contains 2 LRR (leucine-rich) repeats. LRRC25 may be involved in the activation of cells of innate and acquired immunity.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus.
Database links:
Entrez Gene: 126364 Human
Entrez Gene: 211228 Mouse
Omim: 607518 Human
SwissProt: Q8N386 Human
SwissProt: Q8K1T1 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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