| 產(chǎn)品編號(hào) | bs-41107R-AP |
| 英文名稱 | Rabbit Anti-Myoglobin/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的肌紅蛋白抗體 |
| 別 名 | MYO; MB; MGC13548; PVALB; MYG_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 免疫學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 17kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Purified Human Myoglobin (Natural Human Myoglobin protein) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | Constituents: 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3, 50% glycerol. Or Lyophilized. Buffer = 0.05M TBS, pH 8.0 with 10mg/ml BSA and 0.05% NaN3. Reconstitute with sterile distilled water. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis. Function: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Similarity: Belongs to the globin family. Database links: Entrez Gene: 4151 Human Entrez Gene: 17189 Mouse Omim: 160000 Human SwissProt: P02144 Human SwissProt: P04247 Mouse Unigene: 517586 Human Unigene: 404074 Mouse Unigene: 40511 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肌紅蛋白存在于肌肉中，心肌中含量特別豐富，，有較高的組織特異性，是橫紋肌的特異性標(biāo)記物，但對(duì)腫瘤的敏感性較差。主要用于橫紋肌腫瘤的診斷與鑒別診斷。少數(shù)惡性中胚葉混合瘤、睪丸畸胎瘤、腎母細(xì)胞瘤亦可見(jiàn)陽(yáng)性表達(dá)。 |
