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Mouse Anti-AD7c-NTP/Cy3 Conjugated antibody (bsm-10818M-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價

產(chǎn)品編號 bsm-10818M-Cy3
英文名稱 Mouse Anti-AD7c-NTP/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的神經(jīng)絲蛋白單克隆抗體
別    名 neuronal thread protein AD7c-NTP; AD7c-NTP.  
Journal
PMID
IF
Application
[IF=5.11] He,et al.Disposable Morpho menelaus Based Flexible Microfluidic and Electronic Sensor for the Diagnosis of Neurodegenerative Disease.(2018) Advanced Healthcare Materials. 7:.  microfluidic chip ;  Human.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細胞凋亡  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 2F5
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:200-800 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human AD7C NTP full length protein
亞    型 IgG1
純化方法 affinity purified by Protein G
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is unusual in that its coding sequence is derived almost entirely from a cluster of different Alu repeat sequences. However, the mRNA and the encoded protein have been shown to be expressed in neurons, and overexpressed in brains with Alzheimer's disease. In vitro studies also demonstrated that abnormal expression of this gene promoted neuritic sprouting and cell death, associated with dementia in Alzheimer's disease.

Database links:

GenBank: AAC08737



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

AD7C-NTP是存在于神經(jīng)元中的一種41Kda的蛋白質(zhì),在AD患者腦內(nèi)選擇性升高,和其病理過程相關(guān),AD7C-NTP基因也只在神經(jīng)元表達,AD患者腦脊液中AD7C-NTP表達升高, AD7C-NTP作為AD早期診斷和確診的生物化學(xué)標(biāo)志正引起越來越多的關(guān)注.
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation: Anti-AD7c-NTP Antibody, conjugated (bsm-10818M-Cy3) 1:400, 1.5 hours at 37°C; DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.
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