| 產(chǎn)品編號 | bs-20422R-Gold |
| 英文名稱 | Rabbit Anti-Neogenin/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的神經(jīng)細胞粘附蛋白NGN抗體 |
| 別 名 | NGN; Neo1; Neo 1; Neogenin; NEO1_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細胞生物 神經(jīng)生物學(xué) 細胞粘附分子 細胞分化 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 156kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Neogenin |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: This gene encodes a cell surface protein that is a memberof the immunoglobulin superfamily. The encoded protein consists offour N-terminal immunoglobulin-like domains, six fibronectin typeIII domains, a transmembrane domain and a C-terminal internaldomain that shares homology with the tumor suppressor candidategene DCC. This protein may be involved in cell growth anddifferentiation and in cell-cell adhesion. Defects in this gene areassociated with cell proliferation in certain cancers. Alternatesplicing results in multiple transcript variants. [provided byRefSeq, Feb 2010]. Function: Neogenin is one of several netrin-binding proteins. Neogenin functions as an Repulsive Guidance Molecule (RGM) receptor; RGM is implicated in axonal guidance and neural tube closure. Subunit: Interacts with RGMA. Interacts with MYO10 Subcellular Location: Cell membrane; Single-pass type I membraneprotein. Tissue Specificity: Widely expressed and also in cancer celllines. Similarity: Belongs to the immunoglobulin superfamily. DCC family. Contains 6 fibronectin type-III domains. Contains 4 Ig-like C2-type (immunoglobulin-like)domains. Database links: Entrez Gene: 4756 Human Entrez Gene: 18007 Mouse Omim: 601907 Human SwissProt: Q92859 Human SwissProt: P97798 Mouse Unigene: 388613 Human Unigene: 42249 Mouse Unigene: 10667 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
