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Rabbit Anti-OIP-5/CT86/Gold Conjugated antibody (bs-8856R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-8856R-Gold
英文名稱 Rabbit Anti-OIP-5/CT86/Gold Conjugated antibody
中文名稱 膠體金標記的癌/睪丸抗原抗體86抗體
別    名 5730547N13Rik; Cancer/testis antigen 86; CT 86; CT86; hMIS18beta; LAP2alpha interactor 25; LINT 25; LINT25; MIS18B; MIS18beta; MS18B_HUMAN; OIP 5; OIP-5; OIP5; Opa interacting protein 5; Opa-interacting protein 5; Protein Mis18-beta.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  信號轉導  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OIP-5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
OIP5 is a 229 amino acid nuclear protein that is required for chromosome segregation during mitosis. OIP5 exists as a homodimer but can also heterodimerize with FASP1 (FAPP1-associated protein 1). Essential for the recruitment of CENP-A (centromere autoantigen A) to centromeres, OIP5 localizes to centromeres of interphase cells during late anaphase and G1. The gene encoding OIP5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Function:
Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.

Subcellular Location:
Nucleus. Chromosome. Chromosome, centromere. Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.

Database links:

Entrez Gene: 11339 Human

Omim: 606020 Human

SwissProt: O43482 Human

Unigene: 661645 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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