| 產(chǎn)品編號(hào) | bs-5711R-BF488 |
| 英文名稱 | Rabbit Anti-CCDC106/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的卷曲螺旋結(jié)構(gòu)域蛋白106抗體 |
| 別 名 | Ccdc106; Coiled-coil domain-containing protein 106; Protein predicted by clone 23882; ZNF581; CC106_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCDC106 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Promotes the degradation of p53/TP53 protein and inhibits its transactivity. Function: Promotes the degradation of p53/TP53 protein and inhibits its transactivity. Subunit: Interacts with p53/TP53. Subcellular Location: Nucleus. Note=Colocalizes with p53/TP53. Database links: Entrez Gene: 29903 Human Entrez Gene: 232821 Mouse Omim: 613478 Human SwissProt: Q9BWC9 Human SwissProt: Q3ULM0 Mouse Unigene: 82482 Human Unigene: 482157 Mouse Unigene: 488775 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CCDC106通過(guò)與p53蛋白相互作用，促進(jìn)p53蛋白的降解，導(dǎo)致p53功能失活。CCDC106基因很可能是一個(gè)癌基因，CCDC106的高表達(dá)可能是導(dǎo)致具有野生型p53腫瘤發(fā)生的原因之一。 |
