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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-CSP/Biotin Conjugated antibody (bs-0848R-Bio)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0848R-Bio
英文名稱(chēng)1 Rabbit Anti-CSP/Biotin Conjugated antibody
中文名稱(chēng) 生物素標(biāo)記的環(huán)子孢子蛋白(約氏瘧原蟲(chóng))抗體
別    名 circumsporozoite protein (Plasmodium yoelii); Circumsporozoite protein; CS; CSP_PLAYO.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 昆蟲(chóng)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 37kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from the middle of Plasmodium yoelii CSP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
No data available.

Function:
The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host).

Similarity:
Belongs to the plasmodium circumsporozoite protein family.
Contains 1 TSP type-1 domain.

Database links:
UniProtKB/Swiss-Prot: P06914.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

瘧原蟲(chóng)的保護(hù)性抗原主要在蟲(chóng)體表面,統(tǒng)稱(chēng)表面抗原。在瘧原蟲(chóng)生活史的發(fā)育各期,既有共同抗原,又有期特異性抗原,近年來(lái)經(jīng)研究發(fā)現(xiàn)了惡性瘧原蟲(chóng)和間日瘧原蟲(chóng)的配子表面的保護(hù)性抗原,已證明成熟子孢子體外附著的環(huán)子孢子蛋白(Circumsporozoite  protein,CSP)具有明顯的抗原性。
紅內(nèi)期瘧原蟲(chóng)的不同發(fā)育階段,其抗原的質(zhì)和量均有變化,并可在被寄生的紅細(xì)胞膜上表露出來(lái)。裂殖子和子孢子均屬游離的瘧原蟲(chóng),因此誘導(dǎo)的宿主免疫均較明顯。已知有許多瘧原蟲(chóng)抗體可作用于裂殖子,使裂殖子凝集,阻止裂殖體釋放裂殖子。裂殖子表面抗原與其侵入紅細(xì)胞有關(guān)。
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