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Rabbit Anti-IGSF10/BF488 Conjugated antibody (bs-9200R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9200R-BF488
英文名稱1 Rabbit Anti-IGSF10/BF488 Conjugated antibody
中文名稱 BF488標記的免疫球蛋白超家族成員10抗體
別    名 Adlican2; Calvaria mechanical force protein 608; CMF608; IGS10_HUMAN; IgSF10; Immunoglobulin superfamily member 10.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  細胞周期蛋白  細胞表面分子  細胞分化  細胞骨架  細胞外基質  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 288kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IGSF10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation. The gene encoding IGSF10 maps to chromosome 3, which comprises over 1,100 genes that include a chemokine receptor gene cluster as well as a variety of human cancer related loci.

Function:
May be involved in the maintenance of osteochondroprogenitor cells pool (By similarity).

Subcellular Location:
Secreted

Similarity:
Contains 12 Ig-like C2-type (immunoglobulin-like) domains.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 285313 Human

SwissProt: Q6WRI0 Human

Unigene: 58561 Human

Unigene: 727746 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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