產(chǎn)品編號 |
bs-0689R-Gold |
英文名稱 |
Rabbit Anti-PEPT1/Gold Conjugated antibody
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中文名稱 |
膠體金標記的腸道肽轉運蛋白1/小肽轉運蛋白1抗體 |
別 名 |
SLC15A1; Oligopeptide transporter, small intestine isoform; Peptide transporter 1; Intestinal H(+)/peptide cotransporter; Solute carrier family 15 member 1(SLC15A1); +peptide cotransporter; HPECT1; HPEPT1; Human peptide transporter (HPEPT1) mRNA complete cds; Intestinal H; Oligopeptide transporter small intestine isoform; PEPT1; Peptide transporter 1; Solute carrier family 15 (oligopeptide transporter) member 1; S15A1_HUMAN. |
規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
說 明 書 |
100ul(10nm 15nm 35nm)
|
研究領域 |
信號轉導 通道蛋白 |
抗體來源 |
Rabbit |
克隆類型 |
Polyclonal |
交叉反應 |
Human,
(predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, )
|
產(chǎn)品應用 |
IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
分 子 量 |
79kDa |
性 狀 |
Lyophilized or Liquid |
濃 度 |
0.4mg/ml |
免 疫 原 |
KLH conjugated synthetic peptide derived from human PEPT1 |
亞 型 |
IgG |
純化方法 |
affinity purified by Protein A |
儲 存 液 |
0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 |
Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: PEPT1(Oligopeptide transporter, small intestine isoform (Peptide transporter 1) (Intestinal H(+)/peptide cotransporter) (Solute carrier family 15 member 1) Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products. Subcellular Location:membrane; Multi-pass membrane protein. Tissue Specificity Intestine, kidney, liver and low in brain. Belongs to the PTR2/POT transporter (TC 2.A.17) family.
Function: Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products.
Subcellular Location: Membrane; Multi-pass membrane protein.
Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family.
Database links:
Entrez Gene: 6564 Human
Omim: 600544 Human
SwissProt: P46059 Human
Unigene: 436893 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
小肽轉運蛋白又稱寡肽轉運蛋白;
小肽是蛋白質(zhì)在動物體內(nèi)消化的主要產(chǎn)物,而位于小腸刷狀緣膜上的小肽轉運蛋白 在小肽的吸收過程中發(fā)揮重要作用,因此PepT1的活性直接影響小肽的吸收。
PepT1主要在消化道中表達,在腎臟中也有微弱的表達。PepT1是低親和力、高容量的肽載體PepT2是高親和力、低容量的肽載體。PepT2主要在腎臟中表達。
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