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Rabbit Anti-HCV NS5A transactivated protein 8/AP Conjugated antibody (bs-8158R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8158R-AP
英文名稱 Rabbit Anti-HCV NS5A transactivated protein 8/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的丙肝病毒NS5A反轉(zhuǎn)錄蛋白8抗體
別    名 BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)菌及病毒  細(xì)胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BTBD1/HCV NS5A transactivated protein 8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.

Function:
Probable substrate-specific adapter of an E3ubiquitin-protein ligase complex which mediates the ubiquitinationand subsequent proteasomal degradation of target proteins.

Subunit:
Interacts with topoisomerase 1 and with TRIM5 isoformDelta. Interacts with CUL3.

Subcellular Location:
Cytoplasm, P-body. Note=Cytoplasmic bodies.

Tissue Specificity:
Ubiquitous; higher levels in heart andskeletal muscle.

Similarity:
Contains 1 BTB (POZ) domain.

Database links:
UniProtKB/Swiss-Prot: Q9H0C5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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