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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-CD94/PE-Cy3 Conjugated antibody (bs-2521R-PE-Cy3)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-2521R-PE-Cy3
英文名稱1 Rabbit Anti-CD94/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的NK細(xì)胞表面抑制性受體CD94抗體
別    名 Killer cell lectin-like receptor subfamily D member 1; CD 94; CD94 antigen; KLRD 1; KLRD1; KLRD1 protein; KP 43; KP43; Natural killer cells antigen CD94; NK cell receptor; KLRD1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 免疫學(xué)  細(xì)胞膜受體  細(xì)胞類型標(biāo)志物  自然殺傷細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Rat, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD94
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].

Function:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Subunit:
Can form disulfide-bonded heterodimer with NKG2 family members.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Natural killer cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 3824 Human

Omim: 602894 Human

SwissProt: Q13241 Human

Unigene: 524251 Human

Unigene: 562457 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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