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Rabbit Anti-NEGR1/AP Conjugated antibody (bs-11095R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11095R-AP
英文名稱 Rabbit Anti-NEGR1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的神經(jīng)生長調(diào)節(jié)蛋白1抗體
別    名 A kindred of IgLON; DMML2433; IgLON family member 4; IGLON4; KILON; Neuronal growth regulator 1; Neurotractin; Ntra; PRO4993; UNQ2433; NEGR1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 發(fā)育生物學  神經(jīng)生物學  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NEGR1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
NEGR1 is a 354 amino acid protein belonging to the IgLON family and immunoglobulin superfamily. NEGR1 may play a role in cell adhesion and regenerative axon sprouting in the mammalian brain and is highly expressed in adult hippocampus, cerebrum and brainstem, with much lower levels found in cerebellum. Localizing to the cell membrane at the glycosylphosphatidylinositol anchor (GPI) anchor, NEGR1 contains three Ig-like C2-type (immunoglobulin-like) domains. NEGR1 is encoded by a gene that maps to human chromosome 1p31.1, and is one of several loci associated with body mass index (BMI), possibly contributing to the development of obesity.

Function:
NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor

Similarity:
Belongs to the immunoglobulin superfamily. IgLON family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 257194 Human

Entrez Gene: 320840 Mouse

Entrez Gene: 59318 Rat

Omim: 613173 Human

SwissProt: Q7Z3B1 Human

SwissProt: D3Z4T6 Mouse

SwissProt: D4A2V0 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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