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Rabbit Anti-ox-LDL/PE-Cy7 Conjugated antibody (bs-8574R-PE-Cy7)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-8574R-PE-Cy7
英文名稱 Rabbit Anti-ox-LDL/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的氧化低密度脂蛋白抗體
別    名 ox-LDL; LDL (Copper oxidized); Cu2SO4 oxidized low density lipoprotein; oxidized low density lipoprotein; Low density lipoprotein; MDA oxidized LDL; MDA oxidized low density lipoprotein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  免疫學(xué)  脂蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Mouse, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 Mouse Cu2+ oxidised low density lipoprotein
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.

Subcellular Location:
Secreted.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

氧化低密度脂蛋白是低密度脂蛋白(low density lipoprotein,LDL)經(jīng)氧化修飾后形成的,經(jīng)研究認(rèn)為:OXLDL的增高與動(dòng)脈粥樣硬化性心血管病(Arteriosclerosis cardiovascular disease,ASCVD)的發(fā)生有密切關(guān)系。
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