| 產(chǎn)品編號(hào) | bs-9471R-Gold |
| 英文名稱(chēng) | Rabbit Anti-MESP1/Gold Conjugated antibody |
| 中文名稱(chēng) | 膠體金標(biāo)記的心血管發(fā)育中胚層相關(guān)蛋白1抗體 |
| 別 名 | bHLHc5; Class C basic helix-loop-helix protein 5; Mesoderm posterior 1; Mesoderm posterior 1 homolog; Mesoderm posterior protein 1; MESP 1; Mesp1; MESP1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 心血管 轉(zhuǎn)錄調(diào)節(jié)因子 表觀(guān)遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 30kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MESP1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: MESP1, also known as bHLHc5, is a 268 amino acid protein that contains one basic helix-loop-helix (bHLH) domain, a motif that mediates protein dimerization and can bind to the E-box sequence of DNA. Localized to the nucleus, MESP1 functions as a transcription factor that, via its bHLH domain, participates in the epithelialization and the development of the cardiac and somitic mesoderm. MESP1 is highly expressed during gastrulation and somitogenesis and is necessary for the formation of single heart tubes during cardiac maturation. Early detection of MESP1 may be an indicator of the formation of cardiac precursor cells in developing embryos. Additionally, MESP1 plays a role in the rostrocaudal patterning of the somites, an event that influences select Notch signaling pathways. Function: Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways. Subcellular Location: Nucleus. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Database links: Entrez Gene: 55897 Human Omim: 608689 Human SwissProt: Q9BRJ9 Human Unigene: 447531 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
