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產(chǎn)品中心-北京博奧森生物技術(shù)有限公司
Rabbit Anti-SERBP1/Biotin Conjugated antibody (bs-6734R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6734R-Bio
英文名稱1 Rabbit Anti-SERBP1/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的纖溶酶原激活物抑制劑1 RNA結(jié)合蛋白抗體
別    名 CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI 1 mRNA binding protein; PAI RBP1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1 mRNA binding protein 1; PAIRB_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  腫瘤細(xì)胞生物標(biāo)志物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SERBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
SERBP1 (Plasminogen activator inhibitor 1 RNA-binding protein) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3’-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. SERBP1 interacts with CHD3 and is localized in cytoplasmic and nuclear. It is expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.

Function:
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.

Subunit:
Interacts with CHD3 and TDRD3.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.

Tissue Specificity:
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.

Database links:

Entrez Gene: 26135 Human

Entrez Gene: 66870 Mouse

Entrez Gene: 246303 Rat

Omim: 607378 Human

SwissProt: Q8NC51 Human

SwissProt: Q9CY58 Mouse

SwissProt: Q6AXS5 Rat

Unigene: 530412 Human

Unigene: 240490 Mouse

Unigene: 440861 Mouse

Unigene: 203108 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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