| 產(chǎn)品編號(hào) |
bs-0765R-Cy3 |
| 英文名稱(chēng) |
Rabbit Anti-CD3E/Cy3 Conjugated antibody
|
| 中文名稱(chēng) |
Cy3標(biāo)記的CD3/CD3-ε 抗體 |
| 別 名 |
CD3 epsilon;
CD3e;
CD3e antigen epsilon polypeptide (TiT3 complex);
CD3E antigen epsilon polypeptide;
CD3E antigen, epsilon subunit;
CD3e molecule epsilon;
CD3e molecule, epsilon (CD3 TCR complex);
CD3e molecule, epsilon (CD3-TCR complex);
CD3E_HUMAN;
IMD18;
T cell antigen receptor complex epsilon subunit of T3;
T cell surface antigen T3/Leu 4 epsilon chain;
T cell surface glycoprotein CD3 epsilon chain;
T-cell surface antigen T3/Leu-4 epsilon chain;
T-cell surface glycoprotein CD3 epsilon chain;
T3E;
TCRE. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) |
100ul
|
| 研究領(lǐng)域 |
腫瘤 細(xì)胞生物 免疫學(xué) 干細(xì)胞 細(xì)胞膜受體 細(xì)胞表面分子 淋巴細(xì)胞 t-淋巴細(xì)胞 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類(lèi)型 |
Polyclonal |
| 交叉反應(yīng) |
Human, Mouse,
(predicted: Rat, MACFA)
|
| 產(chǎn)品應(yīng)用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
20kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from mouse CD3E |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Function:
The CD3 complex mediates signal transduction.
Subunit:
The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 1 ITAM domain.
Database links:
Entrez Gene: 916 Human
Entrez Gene: 12501 Mouse
Omim: 186830 Human
SwissProt: P07766 Human
SwissProt: P22646 Mouse
Unigene: 3003 Human
Unigene: 210361 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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