產(chǎn)品編號(hào) | bsm-63312R |
英文名稱 | phospho-MCM2 (S27) Recombinant Rabbit mAb |
中文名稱 | 磷酸化MCM2蛋白重組兔單抗 |
別 名 | BM28; CCNL1; cdc19; CDCL1; Cyclin like 1; MCM2. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 1H6 |
交叉反應(yīng) | Human,Mouse,Rat |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 102 kDa |
檢測(cè)分子量 | 125 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human MCM2 around the phosphorylation site of S27 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. SWISS: P49736 Gene ID: 4171 微小染色體維持缺陷蛋白2又稱微型染色體維持蛋白2或絲裂蛋白,MCM-2是細(xì)胞周期階段的特異性標(biāo)志物,在進(jìn)入細(xì)胞周期的細(xì)胞中均有表達(dá),在細(xì)胞的增值、分化中起到一定的作用 |