產(chǎn)品編號(hào) | bsm-63272R |
英文名稱 | phospho-Src (Y529) Recombinant Rabbit mAb |
中文名稱 | 磷酸化Src原癌基因重組兔單抗 |
別 名 | ASV; Avian sarcoma virus; c SRC; cSrc; EC 2.7.10.2; Neuronal CSRC tyrosine specific protein kinase; Neuronal proto-oncogene tyrosine-protein kinase Src; Neuronal SRC; Oncogene SRC; p60 Src; pp60c src; pp60csrc; Proto oncogene tyrosine protein kinase Src; |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 6H4 |
交叉反應(yīng) | Human,Mouse,Rat |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 60 kDa |
檢測(cè)分子量 | 60 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human Src around the phosphorylation site of Y529 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. SWISS: P12931 Gene ID: 6714 src原癌基因具有酪氨酸激酶活性,參與調(diào)節(jié)正常細(xì)胞的生長(zhǎng)與分化,在控制細(xì)胞增殖的信息轉(zhuǎn)導(dǎo)途徑中起作用;src原癌基因同樣有活化癌基因的作用,能夠誘導(dǎo)細(xì)胞的異常增殖和導(dǎo)致腫瘤發(fā)生。 |