產(chǎn)品編號(hào) | bsm-41411M-HRP |
英文名稱(chēng) | Mouse Anti-SARS-CoV-2 (2019-nCoV) Nucleocapsid, HRP conjugated antibody |
中文名稱(chēng) | 辣根過(guò)氧化物酶標(biāo)記的SARS冠狀病毒2核衣殼蛋白單克隆抗體 |
別 名 | SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 ncov N Protein; 2019-nCoV nucleocapsid protein. |
Specific References (1) | bsm-41411M-HRP has been referenced in 1 publications.
[IF=6.107] Kate A. Parham. et al. Monovalent and trivalent VSV-based COVID-19 vaccines elicit neutralizing antibodies and CD8+ T cells against SARS-CoV-2 variants. ISCIENCE. 2023 Apr;26:106292 Monkey.
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研究領(lǐng)域 | 細(xì)菌及病毒 |
抗體來(lái)源 | Mouse |
克隆類(lèi)型 | Monoclonal |
克 隆 號(hào) | 1C7 |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 46kDa |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | Recombinant SARS-CoV-2 Nucleocapsid Protein: 1-419/419 |
亞 型 | IgG |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. SWISS: P0DTC9 Gene ID: 43740575 |