| 產品編號 |
bsk12032 |
| 英文名稱 |
Mouse IL-7 ELISA Kit
|
| 中文名稱 |
小鼠白細胞介素7酶聯(lián)免疫試劑盒 |
| 別 名 |
Interleukin-7; Interleukin 7; Interleukin7; IL7; IL 7; IL7_MOUSE; LP-1; Lymphopoietin 1. |
| 克 隆 號 |
|
| 種 屬 |
Mouse |
| 線性范圍 |
31.20 - 2,000 pg/mL |
| 應用范圍 |
S/P/CC |
| 檢測限 |
15 pg/mL |
| 適用樣品基質 |
cell culture supernates, serum, and plasma. |
| 保存條件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 |
Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL7 stimulates the proliferation of CD4+/CD8+ cells. The proliferative response of thymocytes to IL7 is not affected by antibodies to the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors. Mature T cells respond to IL7 and Con A, but not to IL7 alone. In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages. IL7 is expressed by adherent stromal cells from various tissues.
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