| 產(chǎn)品編號 |
bsk11106 |
| 英文名稱 |
Human Serpin E1/PAI-1 ELISA Kit
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| 中文名稱 |
人纖溶酶原激活物抑制劑1酶聯(lián)免疫試劑盒 |
| 別 名 |
SERPINE1; PAI; PAI-1; PAI1; PLANH1; serpin family E member 1 |
| 克 隆 號 |
|
| 種 屬 |
Human |
| 線性范圍 |
0.312 - 20ng/mL |
| 應(yīng)用范圍 |
S/P/CC |
| 檢測限 |
0.15ng/mL |
| 適用樣品基質(zhì) |
cell culture supernates, serum, and plasma. |
| 保存條件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor or serpin E1 is a protein that in humans is encoded by the SERPINE1 gene.PAI-1 is a serine protease inhibitor (serpin) that functions as the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological breakdown of blood clots). It is a serine protease inhibitor (serpin) protein (SERPINE1).The other PAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy. In addition, protease nexin acts as an inhibitor of tPA and urokinase. PAI-1, however, is the main inhibitor of the plasminogen activators.
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