| 產(chǎn)品編號 | bs-21592R |
| 英文名稱 | FOXD2 Rabbit pAb |
| 中文名稱 | 叉頭蛋白D2抗體 |
| 別 名 | Drosphilia Forkhead Homolog Like 17; FKHL 17; Forkhead box protein D2; Forkhead Related Activator 9; Forkhead-related protein FKHL17; Forkhead-related transcription factor 9; FOXD2; FOXD2_HUMAN; FREAC 9; FREAC-9. |
| 研究領(lǐng)域 | 腫瘤 神經(jīng)生物學 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運蛋白 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow) |
| 產(chǎn)品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FOXD2: 71-170/495 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. FOXD1 (also designated Brain Factor 2 or BF-2) is involved in regulating inflammation as well as kidney and retinal development. FOXD1 regulates the activity of NF-AT and NFkB. Deficiency of FOXD1 results in multiorgan, systemic inflammation, exaggerated Th cell-derived cytokine production, and T cell proliferation in autogolgous MLRs. In kidneys, FOXD1 controls the production of signals required for the normal transition of induced mesenchyme into tubular epithelium and full growth and branching of the collecting system. Deletion of FOXD1 results in renal abnormalities. FOXD2 acts as a modulator of T cell activation. Function: Probable transcription factor involved in embryogenesis and somatogenesis. Subcellular Location: Nucleus. Tissue Specificity: Kidney specific. Similarity: Contains 1 fork-head DNA-binding domain. SWISS: O60548 Gene ID: 2306 Database links: Entrez Gene: 2306 Human Entrez Gene: 17301 Mouse Omim: 602211 Human SwissProt: O60548 Human SwissProt: O35392 Mouse Unigene: 166188 Human Unigene: 7997 Mouse |
| 產(chǎn)品圖片 |
Sample:
Jurkat (Human) Cell Lysate at 30 ug
Primary: Anti-FOXD2 (bs-21592R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 49 kD
Observed band size: 49 kD
Sample: Large intestine (Mouse) Lysate at 40 ug Primary: Anti- FOXD2 (bs-21592R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關(guān)于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
