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PRPF4 Rabbit pAb (bs-20098R)  
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產(chǎn)品編號(hào) bs-20098R
英文名稱 PRPF4 Rabbit pAb
中文名稱 PRPF4蛋白抗體
別    名 HPRP4; HPRP4P; PRP4; PRP4 pre mRNA processing factor 4 homolog(yeast); PRP4/STK/WD splicing factor; Prp4p; U4/U6 small nuclear ribonucleoprotein Prp4; WD splicing factor Prp4; PRP4_HUMAN.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRPF4: 431-522/522 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]

Function:
Involved in pre-mRNA splicing.

Subunit:
Interacts directly with PRPF18, PPIH and PRPF3. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. This complex interacts with the U4/U5/U6 tri-snRNP complex.

Subcellular Location:
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.

Similarity:
Contains 7 WD repeats.

SWISS:
Q13523

Gene ID:
8899

Database links:

Entrez Gene: 8899 Human

Entrez Gene: 19134 Mouse

Entrez Gene: 291078 Rat

Omim: 602338 Human

SwissProt: Q08DZ2 Cow

SwissProt: Q13523 Human

SwissProt: Q61136 Mouse

SwissProt: Q5RKH1 Rat

Unigene: 159014 Human

Unigene: 10027 Mouse

Unigene: 482253 Mouse

Unigene: 32654 Rat



產(chǎn)品圖片
Sample: Raji (Human) Cell Lysate at 40 ug HepG2 (Human) Cell Lysate at 40 ug Hela (Human) Cell Lysate at 40 ug Primary: Anti-PRPF4(bs-20098R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 58kD Observed band size: 58kD
Sample: bone (mouse) Lysate at 40 ug lymph node (mouse) Lysate at 40 ug Primary: Anti-PRPF4(bs-200098R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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