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human CD25 Mouse mAb (bsm-30025M)  
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100ug/1880.00元
200ug(PBS only)/5600.00元
大包裝/詢價(jià)

產(chǎn)品編號 bsm-30025M
英文名稱 human CD25 Mouse mAb
中文名稱 小鼠抗人CD25單克隆抗體
別    名 Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; IL2RA_HUMAN.  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 5E9
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 Flow-Cyt=1ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測分子量 55
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD25 
亞    型 Mouse IgG2a, k
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4).
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]

Gene ID:
3559

產(chǎn)品圖片
scatter diagram showing human peripheral blood lymphocytes stained with bsm-30025M. The cells were incubated with the antibody (bsm-30025M, 1ug/Test) for 30 min at room temperature.The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed.
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