| 產(chǎn)品編號 | bs-19403R |
| 英文名稱 | PRPF38A Rabbit pAb |
| 中文名稱 | mRNA前體剪接因子Prp38抗體 |
| 別 名 | 2410002M20Rik; FLJ14936; MGC3320; OTTMUSP00000008592; PR38A_HUMAN; Pre mRNA splicing factor 38A; Pre-mRNA-splicing factor 38A; Prp38; PRP38 pre mRNA processing factor 38(yeast) domain containing A; PRP38 pre mRNA processing factor 38 domain containing A; prpf38a; RGD1311129; RP23-406B13.4; RP5 965L7.1. |
| 研究領(lǐng)域 | 細(xì)胞生物 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse,Rhesus monkey,Gorilla, Orangutan,Xenopus tropicalis) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 37 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRPF38A: 101-200/312 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
HPRP18 is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10. Function: May be required for pre-mRNA splicing. Subcellular Location: Nucleus. Similarity: Belongs to the PRP38 family. SWISS: Q8NAV1 Gene ID: 84950 Database links: Entrez Gene: 456858 Chimpanzee Entrez Gene: 101137881 Gorilla Entrez Gene: 100050749 Horse Entrez Gene: 84950 Human Entrez Gene: 230596 Mouse Entrez Gene: 100171974 Orangutan Entrez Gene: 100356051 Rabbit Entrez Gene: 101115326 Sheep Entrez Gene: 432312 Xenopus laevis Entrez Gene: 549894 Xenopus tropicalis SwissProt: Q8NAV1 Human SwissProt: Q4FK66 Mouse SwissProt: Q5RDD2 Orangutan SwissProt: Q4FZQ6 Xenopus laevis SwissProt: Q28H87 Xenopus tropicalis Unigene: 5301 Human Unigene: 157534 Mouse Unigene: 413915 Mouse Unigene: 54468 Xenopus laevis |
