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Rabbit Anti-NLRP14  antibody (bs-19286R)  
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產品編號 bs-19286R
英文名稱 Rabbit Anti-NLRP14  antibody
中文名稱 NLRP14蛋白抗體
別    名 CLR11.2; GC-LRR; LRR and PYD domains-containing protein 14; NACHT; NACHT, leucine rich repeat and PYD containing 14; NACHT, LRR and PYD containing protein 14; NACHT, LRR and PYD domains-containing protein 14; NAL14_HUMAN; Nalp-iota; NALP14; NLR family, pyrin domain containing 14; NLRP14; NOD5; Nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14; PAN8.  
研究領域 細胞生物  信號轉導  細胞凋亡  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 125 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NLRP14: 81-180/1093 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]

Function:
May be involved in inflammation and spermatogenesis.

Tissue Specificity:
Testis-specific.

DISEASE:
In the testis, expressed mainly in A dark spermatogonia, mid and late spermatocytes and spermatids but not in mitotically active A pale and B spermatogonia.

Similarity:
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 11 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.

SWISS:
Q86W24

Gene ID:
338323

Database links:

Entrez Gene: 338323 Human

Omim: 609665 Human

SwissProt: Q86W24 Human

SwissProt: Q6B966 Mouse

Unigene: 449637 Human

Unigene: 618600 Human

Unigene: 35644 Mouse



產品圖片
Sample: DU145(Human) Cell Lysate at 30 ug LOVO(Human) Cell Lysate at 30 ug Primary: Anti-NLRP14 (bs-19286R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 125 kD Observed band size: 125 kD
Sample: Lane 1: Mouse Testis tissue lysates Lane 2: Mouse Ovary tissue lysates Lane 3: Rat Testis tissue lysates Lane 4: Human SiHa cell lysates Lane 5: Human JAR cell lysates Primary: Anti-NLRP14 (bs-19286R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 125 kDa Observed band size: 138 kDa
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