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Ermin Rabbit pAb (bs-14626R)  
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產(chǎn)品編號 bs-14626R
英文名稱 Ermin Rabbit pAb
中文名稱 Ermin蛋白抗體
別    名 ERMN; ERM like protein; Ermin; ERMIN_HUMAN; ermin, ERM-like protein; JN; Juxtanodin; KIAA1189.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  結(jié)合蛋白  細(xì)胞類型標(biāo)志物  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Sheep,Cow)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ermin: 201-284/284 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

Function:
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity).

Subunit:
Binds actin (By similarity).

Subcellular Location:
Cytoplasm; cytoskeleton

Tissue Specificity:
Highly expressed in adult and fetal brain. Expressed at intermediate levels in the lung and liver.

SWISS:
Q8TAM6

Gene ID:
57471

Database links:

Entrez Gene: 57471 Human

Omim: 610072 Human

SwissProt: Q8TAM6 Human

Unigene: 443894 Human



產(chǎn)品圖片
Sample: Cerebrum (Mouse) Lysate at 40 ug Cerebellum (Mouse) Lysate at 40 ug Primary: Anti-Ermin?(bs-14626R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 34 kD
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Ermin) Polyclonal Antibody, Unconjugated (bs-14626R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
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