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GOLGA3 Rabbit pAb (bs-13480R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-13480R
英文名稱 GOLGA3 Rabbit pAb
中文名稱 高爾基體膜相關蛋白抗體
別    名 GCP170; GOLGA 3; GOLGA3; Golgi autoantigen; Golgi complex associated protein of 170 kDa; Golgi complex-associated protein of 170 kD; Golgi membrane associated protein; Golgi peripheral membrane protein; Golgin 160; Golgin subfamily a 3; HGNC:4426; Male enhanced antigen 2; MEA2; SY2/SY10 protein; GOGA3_HUMAN.  
研究領域 細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 167 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GOLGA3/Golgin 160: 951-1050/1498 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The Golgi apparatus consists of a series of stacked, flattened membrane stacks called cisternae that are involved in the transport of lipids and proteins in the secretory pathway and are important for Golgi-microtubule interaction. Golgin 160 is a 1,498 amino acid protein that localizes to both the cytoplasm and to the Golgi apparatus and contains a series of coiled-coil domains. Expressed in a variety of tissues, including heart, liver, testis, kidney, lung and salivary gland, golgin 160 functions as a homodimer that interacts with GOLGA7 and is thought to be involved in maintaining Golgi structure and may play a role in nuclear transport and Golgi apparatus localization. Multiple isoforms of golgin 160 exist due to alternative splicing events.

Function:
GOLGA3 is a member of the golgin family of proteins which are localized to the Golgi. It has been postulated to play a role in nuclear transport and Golgi apparatus localization.

Subunit:
Homodimer. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not.

Subcellular Location:
Cytoplasmic and Golgi Apparatus.

Tissue Specificity:
Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.

Post-translational modifications:
Cleaved by caspases in apoptotic cells.

SWISS:
Q08378

Gene ID:
2802

Database links:

Entrez Gene: 2802 Human

Omim: 602581 Human

SwissProt: Q08378 Human

Unigene: 507333 Human



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