日日操日日操,亚洲一区二区三区四区视频,成人午夜福利激情,无码中文7幕

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
草 B视频,18禁足脚交视频网站www,www看黄片com
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
phospho-STMN1 (Ser63) Rabbit pAb (bs-9764R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)

產(chǎn)品編號(hào) bs-9764R
英文名稱(chēng) phospho-STMN1 (Ser63) Rabbit pAb
中文名稱(chēng) 磷酸化原癌基因蛋白18抗體
別    名 Stathmin 1(phospho S63); p-Stathmin 1(phospho S63); Stathmin 1(phospho-Ser63); Stathmin(phospho Ser63); Stathmin(phospho S63); Lag; LAP 18; LAP18; Leukemia associated phosphoprotein p18; Metablastin; Oncoprotein 18; OP 18; OP18; p18; p19; phosphoprotein 19; phosphoprotein p19; PP17; PP19; PR22; Pr22 protein; Prosolin; Protein Pr22; SMN; Stathmin; Stathmin1; STMN 1; STMN1_HUMAN.  
產(chǎn)品類(lèi)型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse,Rat (predicted: Rabbit,Cow,Chicken)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 16 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Stathmin 1 around the phosphorylation site of Ser63: 41-140/149 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Function:
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear.

Subunit:
Binds to two alpha/beta-tubulin heterodimers. Interacts with KIST.

Subcellular Location:
Cytoplasm, cytoskeleton.

Tissue Specificity:
Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.

Post-translational modifications:
Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization. Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity.

Similarity:
Belongs to the stathmin family.

SWISS:
P16949

Gene ID:
3925

Database links:

Entrez Gene: 3925 Human

Entrez Gene: 16765 Mouse

Entrez Gene: 29332 Rat

Omim: 151442 Human

SwissProt: P16949 Human

SwissProt: P54227 Mouse

SwissProt: P13668 Rat

Unigene: 209983 Human

Unigene: 378957 Mouse

Unigene: 555 Rat



原癌基因蛋白18(oncogene protein 18,Op18),是一種廣泛存在于細(xì)胞質(zhì)的蛋白質(zhì),可與微管蛋白結(jié)合,參與微管和紡錘體的組裝;與細(xì)胞的增殖、分化、再生和運(yùn)動(dòng)均有關(guān),并具有信號(hào)活性調(diào)節(jié)的功能。在細(xì)胞增殖、分化的信號(hào)途徑、傳到通路激活中也具有多種調(diào)節(jié)功能。
近年來(lái)有研究發(fā)現(xiàn),stathmin在多種腫瘤中高表達(dá),并可通過(guò)調(diào)節(jié)微管的解聚,促進(jìn)腫瘤細(xì)胞的運(yùn)動(dòng)及侵襲。Stathmin翻譯后修飾狀態(tài)的改變,可影響與p53蛋白的相互作用,參與腫瘤的發(fā)生發(fā)展.
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse ovary); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (phospho-STMN1 (Ser63)) Polyclonal Antibody, Unconjugated (bs-9764R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat ovary); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (phospho-STMN1 (Ser63)) Polyclonal Antibody, Unconjugated (bs-9764R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (STMN1) Polyclonal Antibody, Unconjugated (bs-9764R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (STMN1) Polyclonal Antibody, Unconjugated (bs-9764R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (STMN1) Polyclonal Antibody, Unconjugated (bs-9764R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Positive control: (mo)Thymocyte (2% Paraformaldehyde-fixed ) Isotype Control Antibody: Rabbit IgG; Dilution: 1μg in 100 μl 1 X PBS containing 0.5% BSA Secondary Antibody: Goat anti-rabbit IgG-FITC; Dilution: 1:200 in 1 X PBS containing 0.5% BSA Primary Antibody: rabbit Anti-phospho-Stathmin 1 (Ser63) (bs-9764R); Dilution: 1μg in 100 μl 1X PBS containing 0.5% BSA
版權(quán)所有 2004-2026 bklrv.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
成年无码DVD| 日韩1区二区三区公司| 国产sm另类在线| 人妻少妇日韩| 捷克一区二区| 日本一区二区视频麻豆传媒| 操丝袜高跟熟女比| 日韩高清精品一区二区| 日韩欧美一级片视频| 国产精品99精品久久免费| 欧美 自拍 偷拍 综合| 亚洲精品安卓无码| 日韩女优精品| 免费的色欲视频| 精品一区二区三区四区麻豆| 蜜臀伊人在亚洲精品一区二区三区| 猛操好看AV大骚逼| 成人超碰精品av| 欧美日韩成人一区有吗在线| 欧美黄片 免费| 小黄书AV一区二区三页| 色香焦成人| 国产黄网一区二区三区| 上少妇视频网站h| 国产又粗又长爽| 国产欧美韩日综日在线免费| 亚洲欧美国产偷拍自拍| 日韩亚洲欧美国产人妻| 黄色短视频亚洲网站在线观看视频| 自拍小青草av| 91香蕉五月婷婷| 艾草成人网在线观看| guochan一区二区三区| 天天弄性久久久久| 日韩少妇性生活网| 免费午夜福利网站| 日本大奶熟妇| 成人一区青青草在线| 射久久久大香蕉| 性生活片乛区二区三区在线播放| 99热免费在线播放|