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EXTL2 Rabbit pAb (bs-6005R)  
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50ul/1180.00元
100ul/1980.00元
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產品編號 bs-6005R
英文名稱 EXTL2 Rabbit pAb
中文名稱 外生性骨疣樣蛋白2抗體
別    名 alpha 1 4 N acetylhexosaminyltransferase EXTL2; alpha GalNAcT EXTL2; Exostoses(multiple) like 2; Exostoses multiple like 2; Exostosin like 2; EXT L2; EXT related protein 2; EXTL 2; EXTR 2; EXTR2; Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase; Multiple exostoses like 2; Processed exostosin like 2; EXTL2_HUMAN.  
研究領域 腫瘤  免疫學  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EXTL: 5-110/330 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and is responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Function:
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type II membrane protein .
Processed exostosin-like 2: Secreted. Note=A soluble form is found in the serum.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the glycosyltransferase 47 family.

SWISS:
Q9UBQ6

Gene ID:
2135

Database links:

Entrez Gene: 2135 Human

Entrez Gene: 58193 Mouse

GenBank: BC045681 Human

Omim: 602411 Human

SwissProt: Q9UBQ6 Human

SwissProt: Q9ES89 Mouse

Unigene: 357637 Human



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