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ANKHD1 Rabbit pAb (bs-5831R)  
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產品編號 bs-5831R
英文名稱 ANKHD1 Rabbit pAb
中文名稱 艾滋病病毒制約錨定蛋白抗體
別    名 ANKH1_HUMAN; ANKHD 1; ANKHD1; Ankyrin repeat and KH domain containing 1; Ankyrin repeat and KH domain containing protein 1; Ankyrin repeat and KH domain-containing protein 1; HIV-1 Vpr-binding ankyrin repeat protein; HIV1 Vpr binding ankyrin repeat protein; hMASK; MASK; Multiple ankyrin repeats single KH domain; Multiple ankyrin repeats single KH domain homolog; VBARP.  
Specific References  (1)     |     bs-5831R has been referenced in 1 publications.
[IF=6.083] Sun, Wenhuizi. et al. Alternative ANKHD1 transcript promotes proliferation and inhibits migration in uterine corpus endometrial carcinoma. NPJ GENOM MED. 2022 Sep;7(1):1-12  IF ;  Human.  
研究領域 腫瘤  細胞生物  免疫學  細菌及病毒  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Pig,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 269 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ANKHD1: 1901-2000/2542 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.

Function:
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.

Subunit:
Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain.

Similarity:
Belongs to the mask family.
Contains 25 ANK repeats.
Contains 1 KH domain.

SWISS:
Q8IWZ3

Gene ID:
54882

Database links:

Entrez Gene: 54882 Human

Omim: 610500 Human

SwissProt: Q8IWZ3 Human

Unigene: 594084 Human

Unigene: 720987 Human



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