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Rabbit Anti-Glypican 4  antibody (bs-2159R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-2159R
英文名稱 Rabbit Anti-Glypican 4  antibody
中文名稱 磷脂酰基醇蛋白聚糖-4抗體
別    名 dJ900E8.1 glypican 4; Glypican proteoglycan 4; Gpc4; K Glypican; Kglypican; OTTHUMP00000024052; Secreted glypican 4; GPC4_HUMAN.  
研究領域 腫瘤  細胞生物  免疫學  神經(jīng)生物學  信號轉(zhuǎn)導  干細胞  細胞凋亡  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Rat (predicted: Mouse,Rabbit,Pig,Cow,Dog,GuineaPig,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1μg/Test,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細胞定位 細胞膜 細胞外基質(zhì) 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Glypican 4: 351-450/556 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]

Function:
Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity).

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side (By similarity).
Secreted glypican-4: Secreted, extracellular space (By similarity).

Similarity:
Belongs to the glypican family.

SWISS:
O75487

Gene ID:
2239

Database links:

Entrez Gene: 2239 Human

Entrez Gene: 14735 Mouse

Entrez Gene: 317322 Rat

Omim: 300168 Human

SwissProt: O75487 Human

SwissProt: P51655 Mouse

Unigene: 58367 Human

Unigene: 1528 Mouse

Unigene: 478164 Mouse



產(chǎn)品圖片
Blank control(blue): U-87MG (fixed with 2% paraformaldehyde (10 min). Primary Antibody:Rabbit Anti-Glypican 4 antibody(bs-2159R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.
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