| 產(chǎn)品編號(hào) | bsm-2068M |
| 英文名稱 | Methamphetamine(4D2) Mouse mAb |
| 中文名稱 | 甲基苯丙胺（冰毒）單克隆抗體 |
| 別 名 | d-Desoxyephedrine hydrochloride; d-N; α-Dimethylphenethylamine hydrochloride; Methylamphetamine hydrochloride; METH. |
| 產(chǎn)品類型 | 小分子抗體 |
| 研究領(lǐng)域 | 藥物及化合物 |
| 抗體來(lái)源 | Mouse |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | 4D2 |
| 交叉反應(yīng) | (predicted: Methamphetamine) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 0.14924 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Methamphetamine |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Methamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase. 抗甲基安非他明抗體 過(guò)量的使用冰毒可導(dǎo)致急性中毒。嚴(yán)重者出現(xiàn)精神混亂、性欲亢進(jìn)、焦慮、煩躁、幻覺(jué)狀態(tài)。長(zhǎng)期濫用可造成慢性中毒、體重下降、消瘦、潰瘍、膿腫、指甲脆化和夜間磨牙。靜脈注射方式濫用者可引起各種感染合并癥；包括肝炎、細(xì)菌性心內(nèi)膜炎、敗血癥和艾滋病等。 |
