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GAL Mouse pAb (bs-0017M)  
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產(chǎn)品編號(hào) bs-0017M
英文名稱 GAL Mouse pAb
中文名稱 甘丙肽/神經(jīng)節(jié)肽抗體
別    名 GALA_HUMAN; Galanin peptides; Galanin; Galanin message-associated peptide(GMAP); GAL1; GALN; GLNN; galanin and GMAP prepropeptide; ETL8; GMAP; GAL-GMAP;  
研究領(lǐng)域 心血管  免疫學(xué)  神經(jīng)生物學(xué)  糖尿病  內(nèi)分泌病  
抗體來源 Mouse
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Chicken,Dog,GuineaPig,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 3/13 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GAL: 33-62/123 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).[supplied by OMIM, Jan 2009]

Function:
Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.

Subcellular Location:
Secreted.

Similarity:
Belongs to the galanin family.

SWISS:
P22466

Gene ID:
51083

Database links:

Entrez Gene: 280799 Cow

Entrez Gene: 51083 Human

Entrez Gene: 14419 Mouse

Entrez Gene: 29141 Rat

Omim: 137035 Human

SwissProt: P11242 Cow

SwissProt: P22466 Human

SwissProt: P47212 Mouse

SwissProt: P10683 Rat

Unigene: 278959 Human

Unigene: 4655 Mouse

Unigene: 8929 Rat



神經(jīng)節(jié)肽(Galanin)是由30個(gè)氨基酸殘基組成的神經(jīng)肽。最初認(rèn)為只在相當(dāng)小的背根神經(jīng)節(jié)細(xì)胞群體及脊髓神經(jīng)元中出現(xiàn),后發(fā)現(xiàn)在消化道及胰腺中也廣泛分布。與感覺的調(diào)整有關(guān),對(duì)痛覺傳遞及脊髓興奮起抑制作用,在很多禽類動(dòng)物中有表達(dá),是中樞神經(jīng)系統(tǒng)及內(nèi)分泌胰腺的神經(jīng)調(diào)節(jié)肽。
產(chǎn)品圖片
Tissue/cell: rat spinal cord; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Galanin Polyclonal Antibody, Unconjugated(bs-0017M) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0024) and DAB(C-0010) staining
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